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‘We hope the outcomes of these studies show the rationale for clinical studies of anti-androgen therapies with bladder cancers, specifically in those tumors that eventually test saturated in CD24 expression markedly,’ Theodorescu says. ‘The next step is moving this promising therapy to clinical trials with human individuals.’.. Anti-androgen therapies might advantage bladder cancer patients Androgens regulate protein CD24, necessary for tumor metastasis Bladder cancers sufferers whose tumors express high levels of the protein CD24 have worse prognoses than sufferers with lower CD24. A University of Colorado Cancers Center study released today in the Proceedings of the National Academy of Sciences implies that CD24 expression may depend on androgens – and that anti-androgen therapies like those currently used to take care of prostate cancer may advantage bladder cancer patients.