Last Articles

Can medical center data detect poor performing doctors?

For example, cancer professionals may have high values for several indicators because they perform difficult operations on very ill sufferers, say the authors. The technique needs to be refined to cope with case mix variation therefore. The authors warn of the potential restrictions of statistics also, including poor or missing quality data that can hamper all analyses, and they tension that the interpretation of outlier status continues to be as yet unclear.In MLL, chromosomal rearrangements of the MLL gene result in aberrant recruitment of the DOT1L HMT, which drives the expression of genes that are leukemogenic in the affected patients. Researchers uncovered leukemic cells in vitro to Epizyme’s potent and DOT1L-targeted HMTi, eliminating genetically-defined cellular material bearing the MLL rearrangement selectively. When Epizyme’s substance was administered in vivo within an aggressive disseminated mouse model of MLL, the treatment resulted in statistically significant extension of survival at every dose tested. Related StoriesNew RNA check of blood platelets can be used to identify area of cancerViralytics enters into clinical trial collaboration contract with MSDMeat-rich diet plan may increase kidney malignancy risk MLL is normally a devastating disease that affects both pediatric and adult patients.