District Court in Phoenix.

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These effects occurred in the absence of activation of CD4+ T cells. Immunologic activity was assessed by changes in proliferative capability of HIV-particular CD8+ T cells and verified that AGS-004 was immunogenic in the majority of subjects. The predominant CD8+ central and effector storage T-cell responses induced by AGS-004 were been shown to be IL-12 dependent and were comparable with profiles shown by HIV-infected individuals thought as long-term non-progressors . In the study, the DCs were made of monocytes gathered by leukapharesis acquired from ART-suppressed people, and RNA was derived from their pre-Artwork plasma samples.